Physiology of Addiction

Addiction involves complex physiological processes affecting the brain's reward system. Key neurotransmitters like dopamine play a crucial role; addictive substances often artificially elevate dopamine levels, leading to intense pleasure. Over time, the brain's natural reward pathways become altered, diminishing the effect of everyday rewards and increasing cravings for the substance. Chronic exposure to addictive substances can cause structural changes in the brain, impairing decision-making and impulse control. These neuroadaptations contribute to compulsive behavior and the difficulty of overcoming addiction, as the brain's wiring becomes increasingly oriented towards seeking and using the substance despite adverse consequences.

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